裴科

发布时间:2016年12月13日 来源:制药与食品工程学院 作者:办公室

邮箱:peike_pk@126.com
教育背景:南京中医药大学,中药炮制专业,医学博士
研究方向:中药炮制相关的物质基础变化机理研究
主要课程:药物化学
参与项目:主持一项江苏省普通高校研究生科研创新计划项目:川芎硫熏前后对微循环障碍及血瘀模型的谱效相关性研究;参与两项国家自然科学基金面上项目:种子类中药“逢子必炒”共性规律及特征性成分质量标准研究(批准号81573603);基于中药炮制与复方配伍理论结合的四逆散“疏肝解郁”机制研究(批准号:81673600);参与一项国家自然科学基金青年项目:基于代谢组学与谱效结合的防己黄芪汤益气祛湿作用物质基础研究(81503207)。

代表性研究成果

 [1] Ke Pei, Hao Cai, Xiao Liu, Sicong Tu, Gang Cao, Huan Li, Yingying Zhao, Xiaoqing Song, Yajing Lou, Fengxian Qiao, Baochang Cai. Evaluation of the influence of sulfur fumigation on the pharmacokinetics of four active ingredients in Si Wu Tang. Journal of Separation science, 2015, 38 (1): 25-33. 

[2] Ke Pei, Yu Duan, Hao Cai, Sicong Tu, Fengxian Qiao, Xiaoqing Song, Xiao Liu, Gang Cao, Kailei Fan, Baochang Cai. Ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry combined with statistical analysis for rapidly revealing the influence of sulfur-fumigated Paeoniae Radix Alba on the chemical constituents of Si Wu Tang. Analytical methods, 2015, 7 (22): 9442-9451.

[3] Ke Pei, Hao Cai, Yu Duan, Fengxian Qiao, Sicong Tu, Xiao Liu, Xiaoli Wang, Xiaoqing Song, Kailei Fan, Baochang Cai. Evaluation of the influence of sulfur-fumigated Paeoniae Radix Alba on the quality of Si Wu Tang by chromatographic and chemometric analysis. Journal of Analytical Methods in Chemistry, 2016, Volume 2016, Article ID 8358609, 10 pages. 

[4] 裴科,蔡皓,刘晓,娄雅静,宋晓庆,乔凤仙,蔡宝昌. 川芎硫磺熏蒸前后的傅里叶变换红外光谱鉴别. 中药材,2015,38(7):1393-1399.

[5] Yu Duan1, Ke Pei1(共一作者), Hao Cai, Sicong Tu, Xinwei Cheng, Zhengwei Zhang, Kailei Fan, Fengxian Qiao, Kunming Qin, Baochang Cai. Strategy of integrated evaluation on traditional Chinese medicine as ‘interaction of system to system’ and establishment of novel fuzzy target contribution recognition with herb-pairs, a case study on Astragali Radix-Fructus Corni. Molecular and Cellular Endocrinology, 2016, 434: 219-237. 

[6] Yu Duan1, Ke Pei1(共一作者), Hao Cai, Sicong Tu, Zhengwei Zhang, Xinwei Cheng, Fengxian Qiao, Kailei Fan, Kunming Qin, Xiao Liu, Baochang Cai. Bioactivity evaluation-based ultra high-performance liquid chromatography coupled with electrospray ionization tandem quadrupole-time-of-flight mass spectrometry and novel distinction of multi-subchemome compatibility recognition strategy with Astragali Radix-Fructus Corni herb-pair as a case study. Journal of Pharmaceutical and Biomedical Analysis, 2016, 129: 514-534.